Bleeding from Occult Tumors
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چکیده
THE COMMON USE of anticoagulant drugs in the treatment of thrombotic manifestations has increased the awareness of resulting complications, notably bleeding from the gastrointestinal and the genitourinary tracts. The incidence of such complications has been estimated between 2 and 19 per cent.' Fatal hemorrhage in a series of 1,091 patients was 0.5 per cent.2 3 When a hemorrhage occurs, it is usually attributed to the anticoagulant. This causal relationship is strengthened by the observation that discontinuing the drug, or giving specific antagonists like vitamin K or protamine sulfate, usually results in rapid cessation of the bleeding. Therefore, in many instances no further investigation of the bleeding site is made. Recently, the hospital charts of five patients who bled during anticoagulant therapy were reviewed. In each case, the bleeding was promptly controlled by specific therapy or by discontinuation of the anticoagulant. Further investigation revealed the presence of an unsuspected tumor. Brief summaries of each case are presented.
منابع مشابه
Tumor vs non-tumor origin of occult and obscure gastrointestinal bleeding requiring hospitalization.
AIMS AND BACKGROUND Occult/obscure gastrointestinal bleeding is often problematic to diagnose. It often leads to delayed treatment, a particularly dangerous circumstance when tumor origins are involved. This study reports the six-year experience of an Italian Surgery Center in the identification of the nature (tumor versus non tumor) and site of origin (upper, middle, lower gastrointestinal tra...
متن کاملIs Occult Obscure Gastrointestinal Bleeding a Definite Indication for Capsule Endoscopy? A Retrospective Analysis of Diagnostic Yield in Patients with Occult versus Overt Bleeding
Background/Aim. Usefulness of capsule endoscopy (CE) for diagnosing small-bowel lesions in patients with obscure gastrointestinal bleeding (OGIB) has been reported. Most reports have addressed the clinical features of overt OGIB, with few addressing occult OGIB. We aimed to clarify whether occult OGIB is a definite indication for CE. Methods. We retrospectively compared the cases of 102 patient...
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Occult gastrointestinal bleeding is defined as gastrointestinal bleeding that is not visible to the patient or physician, resulting in either a positive fecal occult blood test, or iron deficiency anemia with or without a positive fecal occult blood test. A stepwise evaluation will identify the cause of bleeding in the majority of patients. Esophagogastroduodenoscopy (EGD) and colonoscopy will ...
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An 80-year-old woman presented with recurrent occult gastrointestinal bleeding requiring blood transfusions. She underwent endoscopy and colonoscopy that failed to identify the cause of bleeding. An enteroscopy revealed duodenal arteriovenous malformation that was cauterized. However, anemia and occult gastrointestinal bleeding recurred. A repeat enteroscopy was negative. A wireless capsule end...
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Address correspondence to: Dr. Henry C. Ho, Yale University, 333 Cedar Street, 1080 LMP, New Haven, CT 06520-8019; Tel: 203-785-7012; Fax: 203-737-1755; E-mail: [email protected] Small bowel tumors are a rare cause of occult gastrointestinal (GI) bleeding, at times requiring hospitalization and blood transfusion. Capsule endoscopy is a commonly used tool for investigation of occult GI bleeding....
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